Littleton's Bed and Breakfast, located on the Maryland's Eastern Shore in Worcester County, offers charming, immaculate accommodations in a restored circa 1860 Second Empire, Victorian, historic home. This historic house, known as the Littleton T. Clark House is listed on the National Registry of Historic Homes. The Bed and Breakfast caters to a diverse clientele that wants personal service, and the hospitality of gracious hosts, comfortable lodging, and a quality breakfast in a historic setting.

Littleton's is located in the historic town of Pocomoke City appropriately dubbed "the friendliest Town on the Eastern Shore". Resting on the banks of the wild and scenic Pocomoke River (within walking distance from the B & B), the town is in close proximity to the Atlantic Beaches, the Chesapeake Bay, museums, shopping, restaurants and numerous locations for outdoor sports such as biking, canoeing, kayaking, hiking, hunting, fishing, crabbing and more. The Eastern Shore is one of the most traveled to destinations for vacations and getaways in the United States.

In 1992 Pam and Walter Eskiewicz began restoring the Littleton Clark House, a historic property on the National Register of Historic Places in Pocomoke City. The house was built around 1860 by a Pocomoke merchant. It was after the restoration that Pam and Walter decided to open the house as a Bed and Breakfast and become Innkeepers.

Littleton's Bed and Breakfast is the only B & B in Pocomoke City. Your hosts, Walter and Pam often serve as concierges in town, pointing visitors in the direction of historic sites and area recreational opportunities, as well as providing information on local history and cultural attractions.