Welcome to the Little Italy Inn! Located near the picturesque San Diego Bay nestled in the heart of Little Italy, San Diego’s Italian cultural village. San Diego’s historic Little Italy is one of a handful of Italian American business districts remaining in North America. San Diego’s Little Italy is unique and growing more successful combining contemporary development with old world charm. Twenty-Three Unique & Individual Rooms!Originally constructed in 1910, today ownership has remodeled this beautiful Inn and preserved its architecture and warmth. Over the years our landmark building has been host to many colorful personalities ...